Fiona Senchyna

The paper develops methods to infer organ aging, senescence, and hallmark scores from blood transcriptomes and facial photographs, showing associations with mortality.

The paper identifies senescent fibroblast heterogeneity in IPF and links it to DNA damage response dysregulation using gene expression analysis.

This study shows that cellular senescence in IPF fibroblasts disrupts antiviral responses, leading to increased viral titers and altered inflammation.

This study shows DNA damage in neurons leads to a senescent-like state similar to Alzheimer's disease, with distinct features from fibroblasts.

The paper identifies a distinct p16INK4a-associated senescence signature in human ovarian tissue through proteogenomic profiling and spatial analysis.

The paper develops StrainSifter to identify concordant bacterial strains between bloodstream isolates and gut microbiota using whole genome sequencing.

This study identifies diverse resistance mechanisms in CRE isolates from a Northern California health system, showing that nucleic acid testing can predict susceptibility to specific beta-lactam combinations.