Imputation of fluid intelligence scores reduces ascertainment bias and increases power for analyses of common and rare variants
David T. Berg, Daniel Shiloh Malawsky, Wei Huang, Petr Danecek, Klaudia Walter, Georgios Kalantzis, Isaac Wade, Duncan S. Palmer, Ewan Birney, Karin J. H. Verweij, Dirk J. A. Smit, Sarah Lindsay, Matthew E. Hurles, Abdel Abdellaoui, Hilary C. Martin
The paper imputes fluid intelligence scores in a large cohort, reducing ascertainment bias and increasing power to detect genetic associations with common and rare variants.
Nature Genetics · Oct 5, 2026Peer-reviewedGenetic & Genomic Medicine