Rapid Biomarker Screening of Alzheimer's Disease by Interpretable Machine Learning and Graphene-Assisted Raman Spectroscopy
Ziyang Wang, Jiarong Ye, Kunyan Zhang, Ding Li, Tomotaroh Granzier-Nakajima, Jeewan C. Ranasinghe, Yuan Xue, Shubhang Sharma, Isabelle Biase, Mauricio Terrones, Se Hoon Choi, Chongzhao Ran, Rudolph E. Tanzi, Xiaolei Huang, Can Martin Zhang, Shengxi Huang
This paper develops a platform combining graphene-assisted Raman spectroscopy and machine learning to rapidly screen Alzheimer's disease biomarkers in mouse brains, achieving 98% classification accuracy.
ACS Nano · Mar 25, 2022Peer-reviewedNeuroscience