Unravelling Form and Function: Improved function of engineered cardiac tissue through extra-cellular anisotropy
J. A. Cyr, M. Colzani, S. Bayraktar, V. Graup, R. Farndale, S. A. Sinha, S. M. Best, R. E. Cameron
This study shows that aligned collagen scaffolds improve cardiac tissue function by enhancing signaling synchronicity and contractility compared to isotropic scaffolds.
bioRxiv · Aug 6, 2021Bioengineering