Connexin-46/50 in a dynamic lipid environment resolved by CryoEM at 1.9 A
J. A. Flores, B. G. Haddad, K. A. Dolan, J. B. Myers, C. C. Yoshioka, J. Copperman, D. M. Zuckerman, S. L. Reichow
This study uses CryoEM to resolve the structure of connexin-46/50 gap junction channels in a lipid environment, revealing how lipid interactions stabilize the channel and influence its function.
bioRxiv · Apr 14, 2020Biophysics