Nucleosides rescue replication-mediated genome instability of human pluripotent stem cells
J. A. Halliwell, T. J. R. Frith, C. J. Price, O. Laing, O. J. Bower, D. Stavish, P. Gokhale, Z. Hewitt, S. El-Khamisy, I. Barbaric, P. W. Andrews
This study shows that exogenous nucleosides reduce replication stress and genomic instability in human pluripotent stem cells by alleviating DNA damage and mitotic errors.
bioRxiv · Nov 23, 2019Cell Biology