Modelling the synergistic effect of bacteriophage and antibiotics on bacteria: killers and drivers of resistance evolution
Q. J. Leclerc, J. A. Lindsay, G. M. Knight
This paper combines in vitro experiments and mathematical modeling to show that phage and antibiotics can either synergistically kill bacteria or drive multidrug-resistant bacteria evolution, depending on timing and concentration.
bioRxiv · Mar 2, 2022Microbiology