Functional succinate dehydrogenase deficiency and loss of ascorbic acid transporter SLC23A1 are pathognomonic adverse features of clear cell renal cancer
R. K. Aggarwal, Y. Zou, R. A. Luchtel, K. Pradhan, N. Ashai, N. Ramachandra, J. Albanese, J.-i. Yang, X. Wang, S. Aluri, S. Gordon, V. Machha, A. Tischer, A. Aboumohamed, B. A. Gartrell, , N. Shenoy
This paper identifies functional succinate dehydrogenase deficiency and loss of SLC23A1 as common adverse features in clear cell renal cell carcinoma, with implications for diagnosis and treatment.
bioRxiv · Jul 5, 2020Cancer Biology