Modulation of P2X4 pore closure by magnesium,potassium, and ATP
k. immadisetty, J. Alencicks, P. Kekenes-Huskey
This study uses molecular dynamics simulations to show that Mg2+ and K+ ions bound to specific sites on P2X4 receptors stabilize or destabilize the open state of the channel depending on ATP binding.
bioRxiv · May 16, 2021Physiology