Author

P. Kekenes-Huskey

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Organism:human· 2 Research Focus:protein folding & dynamics· 2 Approach:biophysical modeling· 1 Approach:experimental assay· 1 Approach:mechanistic / dynamical model· 1 Assay:protein structure· 1 Assay:proteomics· 1

Frequent Co-Authors

k. immadisetty· 2 shared B. Sun· 1 shared E. E. Cho· 1 shared H. Rahmaninejad· 1 shared J. Alencicks· 1 shared J. R. Beach· 1 shared J. Seflova· 1 shared M. P. Pribadi· 1 shared

Activity by Year

2020-2021 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersPhysiology

k. immadisetty

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Crowding within synaptic junctions influence the degradation of adenoside nucleotides by CD39 and CD73 ectonucleotidases

H. Rahmaninejad, T. Pace, P. Kekenes-Huskey

This study shows that crowders in synaptic junctions affect CD39/CD73 enzyme activity, altering ATP and adenosine availability.

bioRxiv · Sep 21, 2021Cell Biology

Inhibitory and Stimulatory Micropeptides Preferentially Bind to Different Conformations of the Cardiac Calcium Pump

S. R. Cleary, X. Fang, E. E. Cho, M. P. Pribadi, J. Seflova, J. R. Beach, P. Kekenes-Huskey, S. L. Robia

The paper shows that inhibitory and stimulatory micropeptides bind to different conformations of the cardiac calcium pump SERCA, with their binding preference depending on intracellular Ca2+ levels.

bioRxiv · Jun 15, 2021Biophysics

Modulation of P2X4 pore closure by magnesium,potassium, and ATP

k. immadisetty, J. Alencicks, P. Kekenes-Huskey

This study uses molecular dynamics simulations to show that Mg2+ and K+ ions bound to specific sites on P2X4 receptors stabilize or destabilize the open state of the channel depending on ATP binding.

bioRxiv · May 16, 2021Physiology

Structural determinants of calcium binding beyond the EF-hand binding site: A study of alpha parvalbumins

K. Immadisetty, B. Sun, P. Kekenes-Huskey

This study investigates the structural factors influencing calcium binding in alpha parvalbumins, finding that both local and non-local protein properties contribute to Ca2+ affinity and Mg2+ selectivity.

bioRxiv · Sep 18, 2020Biophysics