Author

J. Antel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Assay:scRNA-seq· 2 Assay:ATAC-seq· 1 Assay:ChIP-seq· 1 Research Focus:clustering· 1

Frequent Co-Authors

A. Prat· 1 shared B. Misic· 1 shared C. Baufeld· 1 shared C. Faust Akl· 1 shared C. Lee· 1 shared C. P. Couturier· 1 shared C.-C. Chao· 1 shared F. Giovannoni· 1 shared

Activity by Year

2018-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 18 mutual co-author links

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1 shared paperImmunology

A. Prat

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Disease-associated astrocyte epigenetic memory promotes CNS pathology

H.-G. Lee, J. M. Rone, Z. Li, C. Faust Akl, S. W. Shin, J.-H. Lee, L. E. Flausino, F. Pernin, C.-C. Chao, K. L. Kleemann, L. Srun, T. Illouz, F. Giovannoni, M. Charabati, L. M. Sanmarco, , F. J. Quintana

This study identifies an epigenetically controlled memory astrocyte subset that exacerbates CNS pathology in EAE and MS by promoting pro-inflammatory responses.

bioRxiv · Jan 4, 2024Immunology

Vitamin D regulates MerTK-dependent phagocytosis in human myeloid cells

J. Clarke, M. Yaqubi, N. C. Futhey, S. Sedaghat, C. Baufeld, M. Blain, S. Baranzini, O. Butovsky, J. Antel, J. H. White, L. M. Healy

This study shows that vitamin D reduces MerTK expression in myeloid cells, inhibiting phagocytosis and potentially reducing inflammation in multiple sclerosis.

bioRxiv · Feb 6, 2020Immunology

Single-cell RNA-seq reveals that glioblastoma recapitulates normal brain development

C. P. Couturier, S. Ayyadhury, P. U. Le, J. Monlong, G. Riva, R. Allache, S. Baig, X. Yan, M. Bourgey, C. Lee, Y. C. D. Wang, V. W. Yong, M.-C. Guiot, B. Misic, J. Antel, , K. Petrecca

The paper uses single-cell RNA-seq to show glioblastoma recapitulates normal brain development, identifying a conserved trilineage hierarchy with glial progenitor-like cells as the origin of cancer heterogeneity and therapeutic targets.

bioRxiv · Oct 22, 2018 · PreprintCancer Biology