The domain architecture of JBP1 suggests synergy between J-base DNA binding and thymidine hydroxylase activity
A. Adamopoulos, T. Heidebrecht, J. Roosendaal, W. G. Touw, I. Phan, J. Beijnen, A. Perrakis
This paper investigates the domain architecture of JBP1, showing that the JDBD domain enhances thymidine hydroxylation activity by facilitating J-DNA recognition.
bioRxiv · Dec 20, 2018Biochemistry