Author

J. Bourdon

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Approach:statistical model· 2 Assay:ATAC-seq· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1

Frequent Co-Authors

B. BRETIN· 2 shared D. MEISTERMANN· 2 shared G. CASTEL· 2 shared J. FIRMIN· 2 shared L. DAVID· 2 shared S. KILENS· 2 shared S. LOUBERSAC· 2 shared T. FREOUR· 2 shared

Activity by Year

2019-2021 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersCell Biology

B. BRETIN

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Author profile →

3 papers

Recent·Most cited

Chromatin accessibility combined with enhancer clusters activation mediates heterogeneous response to dexamethasone in myeloma cells

V. GABORIT, J. CRUARD, C. Guerin-Charbonnel, J. Derrien, J.-B. Alberge, E. Douillard, N. Roi, M. Devic, L. Campion, F. Westermann, P. Moreau, C. Herrmann, J. Bourdon, F. Magrangeas, S. Minvielle

The paper investigates how chromatin accessibility and enhancer clusters mediate heterogeneous responses to dexamethasone in myeloma cells, showing epigenomic changes linked to transcriptional heterogeneity.

bioRxiv · Sep 6, 2021 · PreprintCancer Biology

Generation of human induced trophoblast stem cells

G. CASTEL, D. MEISTERMANN, B. BRETIN, J. FIRMIN, J. BLIN, S. LOUBERSAC, A. BRUNEAU, S. CHEVOLLEAU, S. KILENS, C. CHARIAU, A. GAIGNERIE, Q. FRANCHETEAU, H. KAGAWA, E. CHARPENTIER, L. FLIPPE, , L. DAVID

This study generates human induced trophoblast stem cells (hiTSC) from post-natal cells using reprogramming and fate conversion, enabling diverse genetic modeling of placental development and disease.

bioRxiv · Sep 15, 2020Cell Biology

Spatio-temporal analysis of human preimplantation development reveals dynamics of epiblast and trophectoderm

D. Meistermann, S. Loubersac, A. Reigner, J. Firmin, V. Francois - - Campion, S. Kilens, Y. Lelievre, J. Lammers, M. Feyeux, P. Hulin, S. Nedellec, B. Bretin, S. Covin, G. Castel, A. Bihouee, , L. David

This study uses transcriptomic pseudotime modeling and spatial data to reveal lineage specification dynamics in human preimplantation embryos, showing TE and ICM differentiation occurs at the blastocyst stage.

bioRxiv · Apr 10, 2019Cell Biology