Temporal Dynamics of Genetically Heterogeneous Extended-Spectrum Cephalosporin Resistant Escherichia coli Bloodstream Infections
W. C. Shropshire, B. Strope, S. Selvaraj Anand, J. Bremer, P. McDaneld, M. M. Bhatti, A. R. Flores, A. Kalia, S. A. Shelburne
This study uses whole genome sequencing to analyze the temporal dynamics and genetic diversity of extended-spectrum cephalosporin-resistant Escherichia coli bloodstream infections in a U.S. cancer center, revealing stable STc131 prevalence and heterogeneous clonal complexes driving infection peaks.
bioRxiv · Feb 7, 2023Microbiology