Author

S. A. Shelburne

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Microbiology· 5

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:E. coli· 3 Assay:whole-genome sequencing· 3 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Research Focus:clustering· 1 Research Focus:differential expression· 1

Frequent Co-Authors

A. Khan· 2 shared A. R. Flores· 2 shared B. M. Hanson· 2 shared C. A. Arias· 2 shared M. M. Bhatti· 2 shared S. R. Simar· 2 shared T. T. Tran· 2 shared W. C. Shropshire· 2 shared

Activity by Year

2023-2024 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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2 shared papersMicrobiology

A. Khan

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Author profile →

5 papers

Recent·Most cited

Emergent emm4 group A Streptococcus evidences a survival strategy during interaction with immune effector cells

C. M. Odo, L. A. Vega, P. Mukherjee, S. Debroy, A. R. Flores, S. A. Shelburne

This study identifies a survival strategy in emm4 group A Streptococcus strains through downregulation of SLO and upregulation of msrAB, enabling better macrophage survival without increased virulence.

bioRxiv · Apr 9, 2024 · PreprintMicrobiology

Cefiderocol heteroresistance associated with mutations in TonB-dependent receptor genes in Pseudomonas aeruginosa of clinical origin

S. L. Egge, S. A. Rizvi, S. R. Simar, M. Alcade-Rico, J. R. Martinez, B. M. Hanson, A. Q. Dinh, R. de Paula Baptista, T. T. Tran, S. A. Shelburne, J. M. Munita, C. A. Arias, M. Hakki, W. R. Miller

This study examines TBDR mutations in P. aeruginosa clinical isolates and their association with cefiderocol resistance and heteroresistance.

bioRxiv · Jan 30, 2024 · PreprintMicrobiology

LiaX is a surrogate marker for cell-envelope stress and daptomycin non-susceptibility in Enterococcus faecium

D. B. Axell-House, S. R. Simar, D. Panesso, S. Rincon, W. R. Miller, A. Khan, O. A. Pemberton, L. Valdez, A. H. Nguyen, K. S. Hood, K. Rydell, A. M. DeTranaltes, M. N. Jones, R. L. Atterstrom, J. Reyes, , C. A. Arias

This study identifies LiaX as a surrogate marker for cell-envelope stress and daptomycin non-susceptibility in Enterococcus faecium and validates its use through ELISA and genomic analysis of clinical isolates.

bioRxiv · Aug 18, 2023 · PreprintMicrobiology

Temporal Dynamics of Genetically Heterogeneous Extended-Spectrum Cephalosporin Resistant Escherichia coli Bloodstream Infections

W. C. Shropshire, B. Strope, S. Selvaraj Anand, J. Bremer, P. McDaneld, M. M. Bhatti, A. R. Flores, A. Kalia, S. A. Shelburne

This study uses whole genome sequencing to analyze the temporal dynamics and genetic diversity of extended-spectrum cephalosporin-resistant Escherichia coli bloodstream infections in a U.S. cancer center, revealing stable STc131 prevalence and heterogeneous clonal complexes driving infection peaks.

bioRxiv · Feb 7, 2023Microbiology

High-level ceftazidime-avibactam resistance in Escherichia coli conferred by the novel plasmid-mediated beta-lactamase CMY-185 variant

W. C. Shropshire, B. T. Endres, J. Borjan, S. L. Aitken, W. C. Bachman, C. L. McElheny, A. Khan, M. M. Bhatti, P. Saharasbhojane, A. Kawai, R. K. Shields, S. A. Shelburne, Y. Doi

The paper identifies a novel CMY-185 beta-lactamase variant in E. coli that confers high-level resistance to ceftazidime-avibactam through specific amino acid substitutions.

bioRxiv · Feb 3, 2023Microbiology