Author

J. C. Bufton

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Biochemistry· 1

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Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1 Approach:statistical model· 1 Assay:structural biology· 1

Frequent Co-Authors

C. Schaffitzel· 1 shared J.-Y. A. Szeto· 1 shared K. T. Powers· 1 shared

Activity by Year

2022-2022 · peak 1/yr

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3 top collaborators · 3 mutual co-author links

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1 shared paperBiochemistry

C. Schaffitzel

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1 paper

Recent·Most cited

Molecular basis of neurodevelopmental disorder-causing mutation in nonsense-mediated mRNA decay factor UPF3B

J. C. Bufton, K. T. Powers, J.-Y. A. Szeto, C. Schaffitzel

This study investigates how a mutation in UPF3B, a NMD factor, causes intellectual disability by reducing its binding affinity to UPF2 and altering NMD activity.

bioRxiv · Apr 3, 2022 · PreprintBiochemistry