Cancer BiologybioRxivPreprint
Multiplexed analysis of a single EV (MASEV) reveals unique biomarker composition with diagnostic impact
J. Spitzberg, S. Ferguson, K. Yang…·R. Weissleder
The paper introduces MASEV, a method for analyzing single EVs, and finds that common EV markers are rare, biomarkers co-occur in few vesicles, affinity purification loses rare subtypes, and deep profiling improves diagnostic potential.
DOI 10.1101/2022.06.17.496607