Birth of an organelle: molecular mechanism of lipid droplet biogenesis
V. Nieto, J. Crowley, D. E. S. Santos, L. Monticelli
This study identifies the molecular mechanism of lipid droplet biogenesis using computer simulations, showing that budding occurs due to membrane asymmetry and seipin's role in stabilizing ER-LD contact sites.
bioRxiv · Jul 28, 2023 · PreprintBiophysics