Author

V. Nieto

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:host-pathogen & immune response· 1 Assay:imaging· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

A. R. Kroken· 2 shared D. J. Evans· 2 shared L. Monticelli· 2 shared S. M. J. Fleiszig· 2 shared C. Hilpert· 1 shared D. E. S. Santos· 1 shared E. J. Jedel· 1 shared E. Jedel· 1 shared

Activity by Year

2022-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 15 mutual co-author links

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2 shared papersMicrobiology

A. R. Kroken

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Birth of an organelle: molecular mechanism of lipid droplet biogenesis

V. Nieto, J. Crowley, D. E. S. Santos, L. Monticelli

This study identifies the molecular mechanism of lipid droplet biogenesis using computer simulations, showing that budding occurs due to membrane asymmetry and seipin's role in stabilizing ER-LD contact sites.

bioRxiv · Jul 28, 2023 · PreprintBiophysics

Intracellular replication of Pseudomonas aeruginosa in epithelial cells requires suppression of the caspase-4 inflammasome

A. R. Kroken, K. A. Klein, P. S. Mitchell, V. Nieto, E. J. Jedel, D. J. Evans, S. M. J. Fleiszig

This study shows that Pseudomonas aeruginosa suppresses the caspase-4 inflammasome to enable intracellular replication in epithelial cells, highlighting a new role for ExoS in inhibiting host cell death.

bioRxiv · Feb 13, 2023 · PreprintMicrobiology

Pseudomonas aeruginosa can diversify after host cell invasion to establish multiple intracellular niches

N. G. Kumar, V. Nieto, A. R. Kroken, E. Jedel, M. R. Grosser, M. E. Hallsten, M. M. E. Metruccio, T. L. Yahr, D. J. Evans, S. M. J. Fleiszig

This study shows Pseudomonas aeruginosa can persist in vacuoles within host cells despite lacking the T3SS, tolerating antibiotics, and contributing to pathogenesis through intracellular diversification.

bioRxiv · Oct 7, 2022Microbiology

Facilitating CG simulations with MAD: theMArtini Database Server

C. Hilpert, L. Beranger, P. C. T. Souza, P. A. Vainikka, V. Nieto, S. J. Marrink, L. Monticelli, G. Launay

The paper introduces MAD, a web server for generating and managing coarse-grained molecular models for simulations using the Martini force field.

bioRxiv · Aug 3, 2022Biophysics