PAS domain of flagellar histidine kinase FlrB exhibits novel architecture, and binds Heme as sensory signal in unconventional fashion
P. Mukherjee, S. Agarwal, S. Basu Mallick, J. Dasgupta
The paper reports the crystal structure of FlrB's PAS domain and identifies heme as a sensory ligand, showing synergistic binding with ATP to regulate flagellar gene transcription in Vibrio cholerae.
bioRxiv · Jun 29, 2023 · PreprintBiophysics