Cell type-specific genetic regulation of expression in the granule cell layer of the human dentate gyrus
Andrew E. Jaffe, DJ Hoeppner, Takeshi Saito, Lou T. Blanpain, Joy Ukaigwe, EE Burke, Ran Tao, Katsunori Tajinda, Amy Deep‐Soboslay, JH Shin, J. E. Kleinman, Daniel R. Weinberger, Mitsuyuki Matsumoto, T. B. Hyde
The paper uses LCM-seq to profile gene expression in the human dentate gyrus granule cell layer, identifying cell type-specific genetic effects and novel schizophrenia-associated variants not detected in bulk RNA-seq.
bioRxiv · Apr 17, 2019 · PreprintNeuroscience