Author

J. Irudayaraj

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Research Focus:cell-cell communication· 1 Research Focus:chromatin & epigenetic regulation· 1 Assay:DNA methylation· 1

Frequent Co-Authors

M. Sands· 4 shared X. Zhang· 3 shared M. La Frano· 2 shared M. Lin· 2 shared T. Jensen· 2 shared C. J. Fields· 1 shared F. Masoud· 1 shared J. Guelfo· 1 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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4 shared papersPharmacology & Toxicology

M. Sands

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4 papers

Recent·Most cited

MicroRNAs and PFAS: A Pilot Study in Blood Collected from Firefighters

X. Zhang, M. Sands, M. La Frano, M. Spinella, F. Masoud, C. J. Fields, Z. Madak-Erdogan, T. Jensen, J. Irudayaraj

This study examines PFAS exposure in firefighters through miRNA sequencing of plasma exosomes and compares results to general population data, finding no significant overall PFAS difference but miRNA expression heterogeneity.

bioRxiv · Apr 5, 2024 · PreprintPharmacology & Toxicology

Kidney toxicology of a novel compound Lithium Bis(trifluoromethanesulfonyl)imide (LiTFSI, ie. HQ-115) used in energy applications: an Epigenetic evaluation

M. Sands, X. Zhang, J. Irudayaraj

This study evaluates the kidney toxicology of LiTFSI (HQ-115) in mice, finding biochemical changes, renal injuries, and epigenetic alterations linked to inflammation and cancer pathways.

bioRxiv · Apr 2, 2024 · PreprintPharmacology & Toxicology

PFAS assessment in fish: samples from Illinois waters

X. Wang, M. Sands, T. Jensen, M. La Frano, M. Lin, J. Irudayaraj

This study assesses PFAS levels in fish from Illinois waterways, finding elevated concentrations in specific areas and species, with implications for human health risks through fish consumption.

bioRxiv · Aug 29, 2023Pharmacology & Toxicology

In vitro toxicity of LiTFSI on Human Renal and Hepatoma Cells

X. Zhang, M. Sands, M. Lin, J. Guelfo, J. Irudayaraj

This study evaluates the cytotoxicity and molecular effects of LiTFSI on human renal and hepatoma cells, finding it less toxic than PFOS and affecting redox, apoptosis, and DNA methylation.

bioRxiv · Aug 15, 2023 · PreprintPharmacology & Toxicology