Reconciling in vitro and in vivo activities of engineered, LacI-based repressor proteins: Contributions of DNA looping and operator sequence variation
S. Tungtur, K. M. Schwingen, J. J. Riepe, C. J. Weeramange, L. Swint-Kruse
The paper compares in vitro and in vivo activities of engineered LacI-based repressor proteins, showing that DNA looping and operator sequence variation significantly affect their function.
bioRxiv · Nov 23, 2018 · PreprintBiochemistry