Author

J. L. Preston

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:differential expression· 1 Organism:mouse· 1 Approach:statistical model· 1

Activity by Year

2020-2020 · peak 1/yr

1 paper

Recent·Most cited

Cancer BiologyBMC CancerPeer-reviewedFeb 14, 2020

Epigenetic loss of heterozygosity of Apc and an inflammation-associated mutational signature detected in Lrig1+/--driven murine colonic adenomas

J. L. Preston

This study identifies genetic and epigenetic changes in murine colonic adenomas driven by Apc loss, revealing hypermutation and a guanine adduct mutation signature.

DOI 10.1186/s12885-020-6616-y

mousebulk RNA-seq

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