The Alphaherpesvirus Latency Associated Promoter 2 (LAP2) Drives Strong Transgene Expression in Peripheral Tissue Depending on Administration Route and AAV Serotype
C. J. Maturana, A. Chan, J. L. Verpeut, E. A. Engel
This study evaluates the effectiveness of the LAP2 promoter in AAV vectors for transgene expression in mouse tissues, showing it is as potent as EF1 but smaller, enabling larger payloads.
bioRxiv · Aug 4, 2022 · PreprintCell Biology