A Trypanosoma cruzi Antigen and Epitope Atlas: deep characterization of antibody specificities in Chagas Disease patients across the Americas
A. D. Ricci, L. E. Bracco, J. M. Ramsey, M. S. Nolan, M. K. Lynn, J. Altcheh, G. Ballering, F. Torrico, N. Kesper, J. C. Villar, J. D. Marco, F. Aguero
This paper identifies antigenic regions and epitopes from Trypanosoma cruzi using peptide arrays and single-residue mutagenesis, revealing private and high-seroprevalence epitopes in Chagas disease patients.
bioRxiv · Aug 19, 2022 · PreprintImmunology