Cellular Uptake and Fate of Cationic Polymer-Coated Nanodiamonds Delivering siRNA: A Mechanistic Study
J. Majer, M. Kindermann, D. Pinkas, D. Chvatil, P. Cigler, L. Libusova
This study investigates the cellular uptake and fate of cationic polymer-coated nanodiamonds delivering siRNA, finding clathrin-mediated endocytosis as the main entry mechanism and effective gene silencing with low toxicity.
bioRxiv · Nov 2, 2023Biophysics