Localization of S1P1 Receptor Signaling in the rat, mouse and human Central Nervous System
J. Martinez-Gardeazabal, G. Pereira-Castelo, M. Moreno-Rodriguez, A. Llorente-Ovejero, M. Fernandez-Martinez, I. Fernandez-Vega, I. Manuel, R. Rodriguez-Puertas
The paper compares S1P1 receptor activity in human, rat, and mouse brains using autoradiography, finding high activity in grey matter regions and suggesting rats as a suitable model for human studies.
bioRxiv · Jan 29, 2024 · PreprintPharmacology & Toxicology