Quantifying the mechanics and growth of cells and tissues in 3D using high resolution computational models.
P. Van Liedekerke, J. Neitsch, T. Johann, E. Warmt, I. Gonzales Valverde, S. Grosser, S. Hoehme, J. Kaes, D. Drasdo
The paper develops a 3D high-resolution cell-based model to study liver regeneration after drug-induced hepatocyte depletion, finding that migration forces required for tissue closure are lower than predicted by center-based models.
bioRxiv · Jan 22, 2019 · PreprintBioengineering