Flap-enabled next-generation capture (FENGC): precision targeted single-molecule profiling of epigenetic heterogeneity, chromatin dynamics, and genetic variation
M. Zhou, N. H. Nabilsi, A. Wang, M.-P. L. Gauthier, K. O. Murray, H. Azari, W. S. Owens, J. R. B. Newman, F. J. Pardo-Palacios, A. Conesa, A. Riva, T. L. Clanton, B. A. Reynolds, P. Concannon, J. O. Brant, , M. P. Kladde
FENGC enables precise, cost-effective targeted sequencing of genetic and epigenetic features by using flap endonuclease to enrich for specific sequences.
bioRxiv · Nov 8, 2022 · PreprintCancer Biology