Spinal Fusion Properties of Mechanically-Reinforced, Osteomodulatory Chitosan Hydrogels
B. T. Darkow, J. P. Herbert, M. J. Messler, A. Grisolano, A. J. Hemmerla, A. D. Kimes, J. Lanza, Y. Sun, J. R. Crim, D. Stensby, C. Wan, D. K. Moore, B. D. Ulery
This study develops a chitosan hydrogel reinforced with cellulose and allograft to improve spinal fusion, showing enhanced compressive strength, biocompatibility, and osteoinductive properties in vitro and in vivo.
bioRxiv · May 26, 2022Bioengineering