Author

J. P. Mahalik

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2

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Research Focus:protein folding & dynamics· 2 Assay:DNA methylation· 1 Approach:mechanistic / dynamical model· 1 Approach:statistical model· 1

Frequent Co-Authors

M. Muthukumar· 2 shared J. Cifello· 1 shared

Activity by Year

2021-2021 · peak 2/yr

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2 top collaborators · 1 mutual co-author link

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2 shared papersBiophysics

M. Muthukumar

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2 papers

Recent·Most cited

BiophysicsbioRxivPreprintJun 21, 2021

Nucleotide Dynamics During Flossing of Polycation-DNA-Polycation through a Nanopore using Molecular Dynamics

M. Muthukumar, J. P. Mahalik

This paper investigates nucleotide dynamics during DNA translocation through a nanopore under alternating voltage, finding that it increases residence time but introduces stochasticity.

DOI 10.1101/2021.06.21.449276

DNA methylationmechanistic / dynamical model

𝕏 PostBluesky

BiophysicsbioRxivPreprintJun 21, 2021

Langevin dynamics simulation of protein dynamics in nanopores at microsecond timescales

M. Muthukumar, J. P. Mahalik, J. Cifello

This paper develops a Langevin dynamics framework to simulate protein dynamics in nanopores, revealing that small changes in nanopore electrostatic potential significantly affect protein dwell time.

DOI 10.1101/2021.06.21.449278

statistical modelprotein folding & dynamics

𝕏 PostBluesky