Accelerated design of Escherichia coli genomes with reduced size using a whole-cell model and machine learning
I. M. Gherman, K. Sharma, J. P. Rees-Garbutt, W. Pang, Z. S. Abdallah, T. E. Gorochowski, C. S. Grierson, L. Marucci
The paper uses a whole-cell model and machine learning to design a reduced E. coli genome with 40% fewer genes, achieving 95% faster computation.
bioRxiv · Oct 30, 2023Bioengineering