Author

L. Marucci

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Organism:E. coli· 1 Research Focus:gene regulatory network inference· 1 Research Focus:genome assembly· 1

Frequent Co-Authors

E. Pedone· 3 shared A. La Regina· 2 shared A. Erten· 1 shared A. Mustafa· 1 shared C. S. Grierson· 1 shared D. di Bernardo· 1 shared F. Aulicino· 1 shared F. Lluis· 1 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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3 shared papersCell Biology

E. Pedone

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Accelerated design of Escherichia coli genomes with reduced size using a whole-cell model and machine learning

I. M. Gherman, K. Sharma, J. P. Rees-Garbutt, W. Pang, Z. S. Abdallah, T. E. Gorochowski, C. S. Grierson, L. Marucci

The paper uses a whole-cell model and machine learning to design a reduced E. coli genome with 40% fewer genes, achieving 95% faster computation.

bioRxiv · Oct 30, 2023Bioengineering

Development of a single layer microfluidic device for dynamic stimulation, culture and imaging of mammalian cells

A. Mustafa, E. Pedone, A. La Regina, A. Erten, L. Marucci

The paper develops a single-layer microfluidic device for long-term mammalian cell culture and dynamic media exchange, demonstrating efficient mixing and dynamic stimulation capabilities.

bioRxiv · Mar 14, 2022Bioengineering

β-catenin perturbations control differentiation programs in mouse embryonic stem cells

E. Pedone, M. Failli, G. Gambardella, R. De Cegli, A. La Regina, D. di Bernardo, L. Marucci

This study shows that moderate β-catenin levels in β-catenin null mouse ESCs promote specific differentiation programs towards mesoderm or endoderm depending on induction timing.

bioRxiv · May 15, 2020Cell Biology

Canonical Wnt pathway controls mESCs self-renewal through inhibition of spontaneous differentiation via β-catenin/TCF/LEF functions

F. Aulicino, F. Sottile, E. Pedone, F. Lluis, L. Marucci, M. P. Cosma

This study shows that canonical Wnt signaling inhibits mESC differentiation by β-catenin/TCF/LEF functions, and that non-functional β-catenin isoforms can rescue self-renewal defects.

bioRxiv · Jun 16, 2019Cell Biology