In-depth characterization of the cisplatin mutational signature in human cell lines and in esophageal and liver tumors
A. Boot, M. N. Huang, A. W. T. Ng, S.-C. Ho, J. Q. Lim, Y. Kawakami, K. Chayama, B. T. Teh, H. Nakagawa, S. G. Rozen
This study identifies the mutational signature of cisplatin in human cell lines and tumors, enabling detection of cisplatin exposure in hepatocellular and esophageal cancers.
bioRxiv · Dec 17, 2017Cancer Biology