BiophysicsbioRxiv
The Smc5/6 complex is a DNA loop extruding motor
B. Pradhan, T. Kanno, M. U. Igarashi…·E. Kim
The paper identifies Smc5/6 as a DNA-loop-extruding motor, showing it extrudes loops via dimerization and ATP hydrolysis at 1 kb/s.
DOI 10.1038/s41586-023-05963-3