The white-footed deermouse, an infection-tolerant reservoir for several zoonotic agents, tempers interferon responses to endotoxin in comparison to the mouse and rat
A. Milovic, J. V. Duong, A. G. Barbour
The paper compares LPS-induced transcriptional responses in white-footed deermice, mice, and rats, finding reduced interferon responses and alternative macrophage activation in deermice.
bioRxiv · Jun 6, 2023 · PreprintMicrobiology