A Virus-Packageable CRISPR Screen Identifies Host Factors Mediating Interferon Inhibition of HIV
M. Ohainle, L. Pendergast, J. Vermeire, F. Roesch, D. Humes, R. Basom, J. J. Delrow, J. Overbaugh, M. Emerman
The paper uses a CRISPR screen to identify host factors that mediate interferon inhibition of HIV replication, finding several restriction factors and novel dependencies.
bioRxiv · Jul 20, 2018Microbiology