Limitations of Busulfan to Create Humanize Mice with an Innate Immune System.
O. Alhawiti, B. Hu, J. Koblinski, C. Guo, J. W. LANDRY
This study evaluates busulfan's effectiveness in preconditioning humanized mice for immune cell engraftment, finding it works well for hIL15-Tg-NSG but not SGM3-NSG mice.
bioRxiv · Jul 15, 2022 · PreprintImmunology