Downregulation of the central noradrenergic system by Toxoplasma gondii infection
I. Alsaady, E. Tedford, M. Alsaad, G. Bristow, S. Kohli, M. Murray, M. Reeves, M. S. Vijayabaskar, S. J. Clapcote, J. Wastling, G. A. McConkey
This study shows that Toxoplasma gondii infection suppresses the noradrenergic system by downregulating DBH, leading to decreased norepinephrine and increased dopamine in infected animals and cells.
bioRxiv · Jun 14, 2018Microbiology