A low dose of simvastatin enhanced the therapeutic efficacy of mesenchymal stem cell (MSC) transplantation in skin wound healing in diabetic mice associated with increases in pAkt, SDF-1, and angiogenesis
S. Sukpat, N. Israsena, J. Wongphoom, P. Ingrungruanglert, T. M. Sim, S. Patumraj
This study shows that low-dose simvastatin improves MSC transplantation efficacy in diabetic wound healing by increasing pAkt, SDF-1, and angiogenesis.
bioRxiv · Sep 9, 2019 · PreprintPhysiology