Disequilibrium between BRCA1 and BRCA2 circular and messenger RNAs plays a role in breast cancer
C. Levacher, M. Viennot, A. Drouet, L. Beaussire, S. Coutant, J.-C. Thery, S. Baert-Desurmont, M. Lae, P. Ruminy, C. Houdayer
The paper develops a method to study circRNAs and mRNAs, finds lower circRNA/mRNA ratios in breast tumors for BRCA1 and BRCA2, and links this disequilibrium to breast cancer.
bioRxiv · Mar 10, 2023 · PreprintCancer Biology