Global survey of secondary metabolism in Aspergillus niger via activation of specific transcription factors
Cameron Semper, Thi Thanh My Pham, Shane Ram, Sylvester Palys, Gregory Evdokias, J.-P. Ouedraogo, Marie-Claude Moisan, Nicholas Geoffrion, Ian D. Reid, Marcos Di Falco, Zachary Bailey, Adrian Tsang, Isabelle Benoit, Alexei V. Savchenko
The paper identifies novel secondary metabolites in Aspergillus niger by overexpressing transcription factors linked to cryptic biosynthetic gene clusters.
PNAS Nexus · Jul 31, 2025Peer-reviewedMicrobiology