SARM1 is responsible for calpain-dependent dendrite degeneration in mouse hippocampal neurons
Takashi Miyamoto, Chaeyoung Kim, Johann Chow, Jason C. Dugas, Jack DeGroot, Alex L. Bagdasarian, Arun P. Thottumkara, Martin Larhammar, Meredith Calvert, Brian M. Fox, Joseph W. Lewcock, Lesley A. Kane
This study shows SARM1 causes calpain-dependent dendrite degeneration in mouse hippocampal neurons, revealing distinct degeneration pathways in axons and dendrites.
Journal of Biological Chemistry · Jan 8, 2024Peer-reviewedNeuroscience