Development of an imaging toolbox to assess the therapeutic potential and biodistribution of macrophages in a mouse model of multiple organ dysfunction
Jack Sharkey, Lorenzo Ressel, Nathalie Brillant, Bettina Wilm, B. Kevin Park, Patricia Murray
The paper develops an imaging toolbox to assess macrophage therapy effects in a mouse model of multi-organ dysfunction, finding limited functional improvement but persistent macrophage biodistribution in kidneys and liver.
bioRxiv · Jul 19, 2018 · PreprintPharmacology & Toxicology