Rational Control of Basal CAR Expression Improves Discrimination in Inducible T Cell Circuits
Daniel Hoces, Jaclyn Ng, Julian Ignacio Perez, Rogelio Antonio Hernández-López
This study improves inducible T cell circuits by reducing basal CAR expression, enhancing discrimination between target and off-target cells.
bioRxiv · Aug 31, 2026 · PreprintSynthetic Biology