Author

Jacob B. Howard

The Ohio State University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1

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Research Focus:benchmarking· 1 Assay:cryo-EM· 1 Approach:deep learning· 1 Assay:metagenomics· 1 Research Focus:protein structure prediction· 1 Approach:statistical model· 1

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Akshaya NarayanasamyiD· 1 shared Steffen LindertiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

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1 shared paperBiochemistry

Akshaya NarayanasamyORCID

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1 paper

Recent·Most cited

Improving Protein Structure Prediction Using Integrative Cryo-EM and Ion Mobility Mass Spectrometry Modeling

Jacob B. Howard, Akshaya Narayanasamy, Steffen Lindert

This paper introduces CRIM, a scoring function combining cryo-EM and IM-MS data to improve monomeric protein structure prediction, showing reduced RMSD and increased TM-score on both simulated and experimental datasets.

Journal of Chemical Theory and Computation · May 14, 2026Peer-reviewedBiochemistry