Akshaya Narayanasamy

This paper introduces CRIM, a scoring function combining cryo-EM and IM-MS data to improve monomeric protein structure prediction, showing reduced RMSD and increased TM-score on both simulated and experimental datasets.

The paper improves protein complex structure prediction by integrating ion mobility mass spectrometry data with AlphaFold and Rosetta, achieving better RMSD values for many complexes.