Sequencing by Expansion (SBX) -- a novel, high-throughput single-molecule sequencing technology
Mark S. Kokoris, Robert N. McRuer, Melud Nabavi, Aaron Jacobs, Marc J. Prindle, Cynthia Cech, Kendall Berg, Taylor Lehmann, Cara Machacek, John C. Tabone, Jagadeeswaran Chandrasekar, Lacey McGee, Matthew Lopez, Tommy Reid, Cara Williams, , Matthew Corning
This paper introduces SBX, a single-molecule sequencing technology that improves nanopore sequencing accuracy and scalability by encoding DNA into Xpandomers with high signal-to-noise reporter codes.
bioRxiv · Feb 19, 2025 · PreprintGenomics