Mapping spatial cell-cell communication programs by tailoring chains of cells for transformer neural networks
Niklas Brunn, Laia Canal Guitart, Kiana Farhadyar, Camila L. Fullio, Jakob Kailer, Tanja Vogel, Maren Hackenberg, Harald Binder
The paper introduces scCChain, a transformer-based framework for mapping spatial cell-cell communication programs in spatial transcriptomics data, identifying hotspots at single-cell and spot resolution.
bioRxiv · Mar 20, 2026 · PreprintBioinformatics